2017 RC-SIRM Symposium and Workshop

Overall Description

Established in 2013, the University of Kentucky's NIH-funded RC-SIRM: Resource Center for Stable Isotope-Resolved Metabolomics presents its 12-day hands-on Workshop , July 24 through August 4, 2017 and its one day Metabolomics Symposium on August 5. RC-SIRM is one of six NIH Regional Comprehensive Metabolomics Resource Cores supported by the NIH Common Fund.
Attendees of the Workshop will gain working knowledge in the application of SIRM to fundamental biochemistry research in the life sciences and bench-to-bedside translational research.
  • ALL EVENTS will occur in the Lee Todd Jr. Building at 789 S. Limestone St. (formerly the BioPharmacy Building) on the campus of the University of Kentucky.

Workshop - Stable Isotope-Resolved Metabolomics: Experimental design, methods, and data analysis

The 12-day workshop is appropriate for graduate students, technicians, post-docs, and faculty who wish to integrate stable isotope-enabled studies of metabolism into their experimental design.
*Attendees of the Workshop will gain working knowledge in the application of SIRM to fundamental biochemistry research in the life sciences and bench-to-bedside translational research.*
  • The hands-on Workshop is limited to 20 participants with relevant background:
    • Applications for the Workshop participation will be accepted until July 13, 2017.
    • Workshop registration is $3,750 and includes the Symposium and on-campus lodging.
  • Some scholarships are available to offset travel costs for students and post-doctoral fellows whose poster abstracts demonstrate excellence in the science of SIRM.
  • NOTE: Attendance at the one-day Symposium is STRONGLY encouraged if you are attending the 12 day Workshop.
The Workshop will feature demonstrations and hands-on wet lab and dry lap practice including:
  • Stable isotope tracer-based biological experiments
  • Cell and tissue processing, polar and non-polar metabolite extraction, and preparation for MS and NMR analysis
  • Data acquisition with the Center’s Mass and NMR Spectrometers
  • Large-scale analysis of MS and NMR data for metabolites and their stable isotope labeling patterns


Application Information

Application deadline for the Workshop is July 17, 2017.
  • The 12-day Workshop registration fee is $3,750.
    • This fee includes the one-day Symposium, 12-day workshop, on-campus lodging, and breakfast and lunch each day.
  • Attendees are responsible for their own travel arrangements and costs.
    • Attendees will be accommodated for the extent of the Workshop on campus.
  • Link for location, and building and room specifics: Haggin Hall
  • Some scholarships are available to offset travel costs and registration cost, for students, post-doctoral scholars and fellows whose poster abstracts demonstrate excellence in the science of SIRM.

NOTE: Attendance at the one-day Symposiumis STRONGLY encouraged if you are attending the 12-day Workshop.
  • Registration for the 2017 RCSIRM Symposium is now open: REGISTER

Symposium - Stable Isotope-Resolved Metabolomics: from bench to bedside

The one-day Symposium on August 5 will feature presentations and poster sessions from leaders using stable isotope-resolved metabolomics (SIRM) as well as other researchers form around the world in a wide range of research.
This is your chance to hear and meet speakers who use stable isotope labeling and other techniques to investigate metabolic changes in many physiological systems and advancing diagnosis and treatment of many clinical conditions, such as GI, and metabolic disorders, and cancer.
  • The Symposium is open to the public.
  • Registration for the Symposium will open at 8:00 am in the Lobby/Atrium newly named the Lee Todd Jr. Building (formerly the Bio Pharmacy Complex).
    • Registration is Free and a continental breakfast, boxed lunch and dinner buffet will be provided free of charge.
  • There will be poster sessions and Sponsor participation.
    • Poster abstract deadline for the Symposium is July 14, 2017.
  • Registration for the 2017 RCSIRM Symposium is now open : REGISTER

Confirmed speakers

  • Brian Clem, PhD, University of Louisville, JG Brown Cancer Center, KY
  • Benjamin Cravatt, PhD, Scripps Research Institute, CA
  • Whei-Mei Teresa Fan, PhD, University of Kentucky, Markey Cancer Center, KY
  • Eyal Gottlieb, PhD, Israel Institute of Technology
  • Douglas Green, PhD, St. Jude Children’s Research Hospital, TN
  • Richard Higashi, PhD, University of Kentucky, Markey Cancer Center, KY
  • W. Marston Linehan, MD, National Cancer Institute, Bethesda, MD
  • Jamey Young, PhD, School of Engineering, Vanderbilt University, TN


Morning Session

  • 8:00 am Registration
    • Poster Assembly
    • Continental Breakfast
  • 8:30 am Introduction and Welcome
    • – Richard M. Higashi, Ph.D, CESB Director, Mass Spectrometry for Center for Environmental & Systems Biochemistry (CESB), University of Kentucky (UKY)
  • 8:35 am Overview and Welcome
    • – Lisa Cassis, Ph.D, Vice President for Research, UKY
  • 8:45 am Session 1: Chair-Teresa Fan, Ph.D, CESB UKY
    • Plenary Lecture: "Activity-bases proteomics – protein and ligand discovery on a global scale"
    • 9:35 am "Targeting the Metabolic Basis of Kidney Cancer”
      • – W. Marston Linehan, MD, Surgeon-in-Chief, National Institute of Health Chief, Urologic Oncology Branch, National Cancer Institute
  • 10:25 am Break
    • Poster Session
  • 10:50 am Session 2: Chair-Andrew Lane, Ph.D, CESB UKY
    • “Exploring lung cancer metabolome: In vivo and ex vivo for individualized medicine”
      • – Teresa Fan, Ph.D, Professor & Edith D. Gardner Chair in Cancer Research, Department of Toxicology & Cancer Biology, Markey Cancer Center, CESB UKY
    • 11:40 am “LC3-associated phagocytosis: Two ancient pathways collide at the interface of immunity, inflammation, and cancer”
      • – Douglas R. Green, Ph.D, Chair, Immunology Department Co-Leader, Cancer Biology Program, Peter C. Doherty Endowed Chair of Immunology, St. Jude Children’s Research Hospital, Memphis TN
  • 12:30 pm Lunch (Pre-Registered Attendees)
    • Poster Session

Afternoon Session

  • 1:40 pm Session 3: Chair-Hunter Moseley, Ph.D, CESB UKY*
    • “Novel stable isotope methods to assess metabolic fluxes using microscale samples”
      • – Jamey Young, Ph.D, Associate Professor of Chemical & Bimolecular Engineering, Associate Professor of Molecular Physiology & Biophysics, Director of Graduate Recruiting in Chemical Engineering, Vanderbilt School of Engineering, Nashville, TN
    • 2:30 pm “Advanced Mass spectrometry for SIRM”
  • 3:20 pm Tea Break
    • Poster Session
  • 4:20 pm Session 4: Chair-Richard Higashi, Ph.D, CESB UKY
    • "The onco-metabolic role and liabilities of the TCA cycle in cancer"
    • 5:10 pm "Control of Tumor Metabolism by Rb"
      • – Brian Clem, Ph.D, Assistant Professor, Director of Graduate Admission, Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine, Louisville, KY
  • 6:00 pm Closing Remarks: Richard Higashi, Ph.D
  • 6:15 pm Adjourn for dinner (Pre-Registered Attendees)

Abstract Submission Guidelines

Abstracts for poster presentations for UK Metabolomics Symposium & Workshop 2017 must be:
  • Submitted by 11:00 pm (EDT) on July 13, 2017, via Word document to Alicia Colliver at ajduna0@email.uky.edu.
  • See Format instructions below.

The Program Committee will review abstracts based on their relationship to human metabolism, novelty, significance of findings and clarity.
  • For questions regarding abstract submission please contact Alicia Colliver at ajduna0@email.uky.edu, or (859)218-1032


The total character count (including the title and list of authors) may not exceed 4000 characters, including spaces; or 1 page, including any graphical content or Table.
Each abstract should be sectionalized as follows:
  • Title and Affiliation- first 6 lines.
    • Line 1: Title - maximum 25 words 14 point Bold Arial or Times New Roman. The title should sufficiently represent the content of the abstract. All keywords necessary to identify the subject matter should be included in the title to facilitate electronic retrieval where applicable. Non-standard abbreviations in the title should be avoided. Remainder 11 point Arial or Times.
    • Line 2: Authors - use superscript numbers to refer to affiliations
    • Line 3: Affiliations
    • Line 4: blank
    • Line 5: Abbreviations used in the body of an abstract should be defined at first use.
      • Complex investigational regimens should be clearly identified.
    • Line 6: blank
  • Background - a brief statement indication the purpose(s) of the study
  • Experimental - a brief description of pertinent experimental procedures used.
  • Results - a clear representation of experimental results.
  • Conclusion a statement of conclusion.
  • Acknowledgements - e.g. funding
  • Bibliography

Sponsors -

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Topic revision: r40 - 07 Mar 2018, HunterMoseley
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