2017 RC-SIRM Symposium and Workshop

Overall Description

• ALL EVENTS will occur in the Lee Todd Jr. Building at 789 S. Limestone St. (formerly the BioPharmacy Building) on the campus of the University of Kentucky.

Workshop - Stable Isotope-Resolved Metabolomics: Experimental design, methods, and data analysis

• The hands-on Workshop is limited to 20 participants with relevant background:
  • Applications for the Workshop participation will be accepted until July 13, 2017.
  • Workshop registration is $3,750 and includes the Symposium and on-campus lodging.
• Some scholarships are available to offset travel costs for students and post-doctoral fellows whose poster abstracts demonstrate excellence in the science of SIRM.
• NOTE: Attendance at the one-day Symposium is STRONGLY encouraged if you are attending the 12 day Workshop.

• Stable isotope tracer-based biological experiments
• Cell and tissue processing, polar and non-polar metabolite extraction, and preparation for MS and NMR analysis
• Data acquisition with the Center’s Mass and NMR Spectrometers
• Large-scale analysis of MS and NMR data for metabolites and their stable isotope labeling patterns

Agenda

• Workshop_Agenda_2017_-_FINAL_-_07.21.17.docx

Application Information

• The 12-day Workshop registration fee is $3,750.
  • This fee includes the one-day Symposium, 12-day workshop, on-campus lodging, and breakfast and lunch each day.
• Attendees are responsible for their own travel arrangements and costs.
  • Attendees will be accommodated for the extent of the Workshop on campus.
• Link for location, and building and room specifics: Haggin Hall
• Some scholarships are available to offset travel costs and registration cost, for students, post-doctoral scholars and fellows whose poster abstracts demonstrate excellence in the science of SIRM.

• Registration for the 2017 RCSIRM Symposium is now open: REGISTER

Symposium - Stable Isotope-Resolved Metabolomics: from bench to bedside

• The Symposium is open to the public.
• Registration for the Symposium will open at 8:00 am in the Lobby/Atrium newly named the Lee Todd Jr. Building (formerly the Bio Pharmacy Complex).
  
  • Registration is Free and a continental breakfast, boxed lunch and dinner buffet will be provided free of charge.
• There will be poster sessions and Sponsor participation.
  • Poster abstract deadline for the Symposium is July 14, 2017.
• Registration for the 2017 RCSIRM Symposium is now open : REGISTER

Confirmed speakers

• Brian Clem, PhD, University of Louisville, JG Brown Cancer Center, KY
• Benjamin Cravatt, PhD, Scripps Research Institute, CA
• Whei-Mei Teresa Fan, PhD, University of Kentucky, Markey Cancer Center, KY
• Eyal Gottlieb, PhD, Israel Institute of Technology
• Douglas Green, PhD, St. Jude Children’s Research Hospital, TN
• Richard Higashi, PhD, University of Kentucky, Markey Cancer Center, KY
• W. Marston Linehan, MD, National Cancer Institute, Bethesda, MD
• Jamey Young, PhD, School of Engineering, Vanderbilt University, TN

Agenda

Morning Session

• 8:00 am Registration
  • Poster Assembly
  • Continental Breakfast
• 8:30 am Introduction and Welcome
  • – Richard M. Higashi, Ph.D, CESB Director, Mass Spectrometry for Center for Environmental & Systems Biochemistry (CESB), University of Kentucky (UKY)
• 8:35 am Overview and Welcome
  • – Lisa Cassis, Ph.D, Vice President for Research, UKY
• 8:45 am Session 1: Chair-Teresa Fan, Ph.D, CESB UKY
  • Plenary Lecture: "Activity-bases proteomics – protein and ligand discovery on a global scale"
    • – Benjamin Cravatt, Ph.D, Department of Molecular Medicine California Campus, The Scripps Research Institute, San Diego CA
      • RCSIRM_Symposium_2017_Benjamin_Cravatt.pdf
  • 9:35 am "Targeting the Metabolic Basis of Kidney Cancer”
    • – W. Marston Linehan, MD, Surgeon-in-Chief, National Institute of Health Chief, Urologic Oncology Branch, National Cancer Institute
• 10:25 am Break
  • Poster Session
• 10:50 am Session 2: Chair-Andrew Lane, Ph.D, CESB UKY
  • “Exploring lung cancer metabolome: In vivo and ex vivo for individualized medicine”
    • – Teresa Fan, Ph.D, Professor & Edith D. Gardner Chair in Cancer Research, Department of Toxicology & Cancer Biology, Markey Cancer Center, CESB UKY
  • 11:40 am “LC3-associated phagocytosis: Two ancient pathways collide at the interface of immunity, inflammation, and cancer”
    • – Douglas R. Green, Ph.D, Chair, Immunology Department Co-Leader, Cancer Biology Program, Peter C. Doherty Endowed Chair of Immunology, St. Jude Children’s Research Hospital, Memphis TN
• 12:30 pm Lunch (Pre-Registered Attendees)
  • Poster Session

Afternoon Session

• 1:40 pm Session 3: Chair-Hunter Moseley, Ph.D, CESB UKY*
  • “Novel stable isotope methods to assess metabolic fluxes using microscale samples”
    • – Jamey Young, Ph.D, Associate Professor of Chemical & Bimolecular Engineering, Associate Professor of Molecular Physiology & Biophysics, Director of Graduate Recruiting in Chemical Engineering, Vanderbilt School of Engineering, Nashville, TN
      • RCSIRM_Symposium_2017_Jamey_Young.pdf
  • 2:30 pm “Advanced Mass spectrometry for SIRM”
    • – Richard Higashi, Ph.D, Professor, Department of Toxicology & Cancer Biology, Markey Cancer Center, CESB UKY
      • RCSIRM_Symposium_2017_Richard_Higashi.pdf
• 3:20 pm Tea Break
  • Poster Session
• 4:20 pm Session 4: Chair-Richard Higashi, Ph.D, CESB UKY
  • "The onco-metabolic role and liabilities of the TCA cycle in cancer"
    • – Eyal Gottlieb, Ph.D, Professor, Director, Laura & Isaac Perlmutter Metabolomics Centre, Technion – Israel Institute of Technology, Haifa, Israel
      • RCSIRM_Symposium_2017_Eyal_Gottlieb.pdf
  • 5:10 pm "Control of Tumor Metabolism by Rb"
    • – Brian Clem, Ph.D, Assistant Professor, Director of Graduate Admission, Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine, Louisville, KY
      • RCSIRM_Symposium_2017_Brian_Clem.pdf
• 6:00 pm Closing Remarks: Richard Higashi, Ph.D
• 6:15 pm Adjourn for dinner (Pre-Registered Attendees)

Abstract Submission Guidelines

Format

• Title and Affiliation- first 6 lines.
  • Line 1: Title - maximum 25 words 14 point Bold Arial or Times New Roman. The title should sufficiently represent the content of the abstract. All keywords necessary to identify the subject matter should be included in the title to facilitate electronic retrieval where applicable. Non-standard abbreviations in the title should be avoided. Remainder 11 point Arial or Times.
  • Line 2: Authors - use superscript numbers to refer to affiliations
  • Line 3: Affiliations
  • Line 4: blank
  • Line 5: Abbreviations used in the body of an abstract should be defined at first use.
    • Complex investigational regimens should be clearly identified.
  • Line 6: blank
• Background - a brief statement indication the purpose(s) of the study
• Experimental - a brief description of pertinent experimental procedures used.
• Results - a clear representation of experimental results.
• Conclusion a statement of conclusion.
• Acknowledgements - e.g. funding
• Bibliography

Sponsors -