March 24: Practical Workshop Belknap Research Building, U of Louisville
8:30 am Session I
Dr. Andrew Lane, Brown Cancer Center, University of Louisville: "Positional Isotopomer analysis by NMR for Metabolic Pathway Tracing"
9:30 am Session II
Dr. Richard Higashi, Department of Chemistry, University of Louisville: "Mass Spectometry Motifs for Metabolomics: an Overview of Approaches"
Dr. Erik Larson, National Food Institute, Technical University of Denmark, Copenhagen: "HPLC or GC coupled with ICP-MS for Targeted Metallo-metabolite Analysis"
Dr. Jack Henion, Advion BioSciences: "Chip-Based Nano Electrospray Mass Spectrometry: Background and Applications for Studies in the Life Sciences."
Dr. Mark Libardoni, LECO Corporation: "Utilizing GC and GCxGC coupled with Time-of-Flight Mass Spectroscopy (TOMFS) for the analysis of Metabolomic Samples"
Dr. Anne Ferguson, Thermo Fisher Scientific: "An Integrated Approach to Metabolomics"
12:30 pm Lunch and Demonstrations
3:30 pm Session III
Dr. Masanori Arita, Dept. of Computational Biology, University of Tokyo: "Database for Flavonoids and Measurement in Arabidopsis"
Dr. Maciek R. Antoniewicz, Department of Chemical Engineering, MIT: "Elementary Metabolite Unites (EMU): A Novel Framework for Modeling Isotopic Tracer Distributions and Determining Metabolic Fluxes"
March 25: Frontiers in Isotopomer Metabolomics, Brown Hotel
8:15 am Session I: Clinical Applications. Chair, Dr. Teresa Fan
Dr. Donald Miller, JG Brown Cancer Center, University of Louisville: "In Vivo Mteabolomic Analysis of Human Lung Cancer."
Dr. Graeme Mason, Psychiatry and Diagnostic Radiology, Yale Magnetic Resonance Research Center, Yale University, School of Medicine: "Evaluations of Metabolic Pathways with 13C Detection"
Dr. Rima Kaddurah Daouk, Dept. of Psychiatry and Behavioral Sciences, Duke University Medical Center: "Metabolomics for Mapping Disease Signatures and Drug Reposonse Phenotypes"
10:45 am Session II: Metabolomics meets other -omics. Chair, Dr. William Pierce
Dr. Dan Liebler, Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt University: "Metabolomics meets Proteomics: Protein Targets of Reactive Lipid Oxidaton Products in Oxidative Stress."
Dr. Lloyd Sumner, The Samuel Robers Noble Foundation: "Integrated Functional Genomic Studies of the Model Legume Medicago truncatula."
1:30 pm Session III: Agency Perspective. Chair, Dr. Rima Kaddurah Daouk
Dr. David Balshaw, Program Director, NIEHS: "Approaches to Addressing Long Standing Issues in the Environmental Health Sciences."
2:15 pm Session IV: Flux Modeling. Chair, Dr. Joanne Kelleher
Dr. Joanne Kelleher, Department of Chemical Engineering, MIT: "Analyusis of Metabolite Labeling using Stable Isotope Tracers Reveals Distinctive Pathway of Glutamine Metabolism in Transformed Cells."
Dr. Marta Cascante, Biochemoinformatics, University of Barcelona: "From the Analysis of Cell Metabolic Adaptation to Rational Drug Development."
Sponsors
ThermoFisher Scientific
Sigma-Aldrich
Advion
LECO
Varian
EPSCOR: Kentucky NSF
James Graham Brown Cancer Center
University of Louisville College of Arts and Sciences